1383849-44-2

Upstream product

• 1383849-42-0 5-(6-bromo-2-phenylquinolin-3-yl)pentanoic acid 
• 7472-43-7 6-benzoylhexanoic acid 
• 29124-57-0 2-amino-5-bromobenzaldehyde 
• 201230-82-2 carbon monoxide 
• 1383849-43-1 tert-butyl 5-(6-bromo-2-phenylquinolin-3-yl)pentanoate 

Relevant academic research and scientific papers

QUINOLINES AND AZA-QUINOLINES AS CRTH2 RECEPTOR MODULATORS

The invention provides certain quinolines and aza-quinolines of the Formula (I), and their pharmaceutically acceptable salts, wherein E, J1, Ja, Jb, R2, R3, R22, Ra, Rb, Rc, Rd, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with with uncontrolled or inappropriate stimulation of CRTH2 function.