138405-07-9

Usage

Isomer

A specific isomer of cyclopentanedimethanol with an amino group attached to the 4th position.

Molecular structure

Cyclic compound with two hydroxyl groups (-OH) and an amino group (-NH2).

Stereochemistry

The stereochemistry of the compound is (1alpha,2beta,4alpha).

Applications

Potential applications in pharmaceuticals, organic synthesis, and material science.

Unique properties

This specific isomer may have unique properties and reactivity compared to other isomers of cyclopentanedimethanol.

Building block

Can be used as a building block for the synthesis of various organic compounds.

Further research

Additional research and experimentation are necessary to fully understand its potential uses and properties.

Upstream product

• 16631-27-9 rac-trans-3,4-bis(methoxycarbonyl)hexanedioic acid 
• 6453-07-2 (+/-)-trans-4-oxo-1,2-cyclopentanedicarboxylic acid bis(methyl ester) 
• 138405-06-8 (+/-)-trans-4-hydroxyimino-1,2-cyclopentanedicarboxylic acid bis(methyl ester) 

Relevant academic research and scientific papers

Divergent synthesis of two precursors of 3′-homo-2′-deoxy- and 2′-homo-3′-deoxy-carbocyclic nucleosides

Aminocyclopentanedimethanols 4 and 5, which are of interest for the synthesis of higher homologues of 2′-deoxy- and 3′-deoxycarbonucleosides, respectively, were efficiently prepared by divergent routes starting from (±)-exo-bicyclo[2.2.1]hept-5-ene-2-carbaldehyde. In the key step, ammonolysis of the common intermediate (±)-(1β,3β,4α)-4-benzoyloxymethyl-1,3- cyclopentanedicarboxylic anhydride and subsequent esterification afford near-equimolar amounts of two easily separable isomeric carbamoyl esters.

SYNTHESIS OF RING-ENLARGED CYCLOBUT-A AND CYCLOBUT-G ANALOGUES AS HIV INHIBITORS. PART 4

Two ring-expanded analogues (compounds 13 and 14) of the anti-HIV agents Cyclobut-A and Cyclobut-G are described.They were synthesized from trans-3,4-bis(hydroxymethyl)cyclobutylamine which was obtained from threo-3,4-bis(methoxycarbonyl)hexane dioic acid.Neither compound (13,14) was able to provide protection to CEM cells against HIV-1-infection.