138407-94-0

Basic information

• Product Name: Cyclohexanemethanol, a-[2-(dimethylphenylsilyl)-1-propenyl]-, (E)-
• CAS NO: 138407-94-0
• Molecular Formula: C18H28OSi
• Molecular Weight: 288.505
• Mol File: 138407-94-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclohexanemethanol, a-[2-(dimethylphenylsilyl)-1-propenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanemethanol, a-[2-(dimethylphenylsilyl)-1-propenyl]-, (E)-(138407-94-0)
• EPA Substance Registry System: Cyclohexanemethanol, a-[2-(dimethylphenylsilyl)-1-propenyl]-, (E)-(138407-94-0)

Safety Data

• Hazardous Substances Data: 138407-94-0(Hazardous Substances Data)

Upstream product

• 130708-18-8 1-Cyclohexyl-3-(dimethylphenylsilyl)prop-2-ynol 
• 74-88-4 methyl iodide 
• 766-77-8 Dimethylphenylsilane 
• 165277-52-1 1-Cyclohexyl-2-butyn-1-ol 
• 3839-31-4 dimethyl(phenyl)silyl lithium 
• 768-33-2 phenyldimethylsilyl chloride 
• 7152-32-1 4-cyclohexyl-3-buten-2-one 

Downstream Products

• 138408-03-4 (1R,3R)-1-Cyclohexyl-3-(dimethyl-phenyl-silanyl)-butan-1-ol 
• 909193-83-5 (Z)-1-cyclohexylbut-2-en-1-ol 
• 79646-42-7 (E)-1-cyclohexyl-2-buten-1-ol 
• 138408-10-3 (1R,3R)-1-Cyclohexyl-butane-1,3-diol 

Relevant articles and documents

Tuning of α-Silyl Carbocation Reactivity into Enone Transposition: Application to the Synthesis of Peribysin D, E-Volkendousin, and E-Guggulsterone

A reliable method for enone transposition has been developed with the help of silyl group masking. Enantio-switching, substituent shuffling, and Z-selectivity are the highlights of the method. The developed method was applied for the first total synthesis of peribysin D along with its structural revision. Formal synthesis of E-guggulsterone and E-volkendousin was also claimed using a short sequence.

PtCl2/XPhos: A highly efficient and readily available catalyst for the hydrosilylation of propargylic alcohols

A highly regioselective hydrosilylation of propargylic alcohols has been developed using an in situ prepared PtCl2/XPhos catalyst system. The reaction is tolerant of many functional groups and exhibits excellent regio and geometric selectivity.