1384186-75-7

Basic information

• Product Name: 2-(4-methoxyphenyl)-2-oxo-N-(2,3,4-trimethoxyphenethyl)acetamide
• Synonyms: 2-(4-methoxyphenyl)-2-oxo-N-(2,3,4-trimethoxyphenethyl)acetamide
• CAS NO: 1384186-75-7
• Molecular Weight: 373.406
• Mol File: 1384186-75-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-2-oxo-N-(2,3,4-trimethoxyphenethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-2-oxo-N-(2,3,4-trimethoxyphenethyl)acetamide(1384186-75-7)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-2-oxo-N-(2,3,4-trimethoxyphenethyl)acetamide(1384186-75-7)

Safety Data

• Hazardous Substances Data: 1384186-75-7(Hazardous Substances Data)

Upstream product

• 3937-16-4 2-(2,3,4-trimethoxyphenyl)ethylamine 
• 13664-92-1 2,2-dibromo-1-(4-methoxyphenyl)ethanone 

Downstream Products

• 5489-20-3 (4-methoxyphenyl)(5,6,7-trimethoxy-3,4-dihydroisoquinolin-1-yl)methanone 

Relevant articles and documents

Synthesis of isoquinoline alkaloids via oxidative amidation-bischler- napieralski reaction

A straightforward synthesis of -keto amides by coupling primary amines with aryl dibromoethanones under oxidative amidation conditions has been developed. The -keto amides were then subjected to heterocyclodehydration reaction under Bischler-Napieralski conditions followed by aromatization with DBU provided 1-benzoyl isoquinolines in a two-stage process. Utilizing this methodology, isoquinoline alkaloids such as thalmicrinone, papavaraldine, and pulcheotine A were synthesized in excellent yields. Georg Thieme Verlag Stuttgart · New York.