1384264-43-0 Usage
General Description
1-(5-chloro-3-fluoropyridin-2-yl)ethanamine is a chemical compound with the molecular formula C7H8ClFN. It is an ethanamine derivative containing a 5-chloro-3-fluoropyridin-2-yl group. 1-(5-chloro-3-fluoropyridin-2-yl)ethanamine is commonly used in pharmaceutical research as a building block for the synthesis of potential drug candidates. Its structure and properties make it useful for the development of new medications, particularly in the field of neuroscience and drug discovery. The chemical may have potential applications in the treatment of various neurological and psychiatric disorders, although further research is needed to fully understand its pharmacological properties and potential therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 1384264-43-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,4,2,6 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1384264-43:
(9*1)+(8*3)+(7*8)+(6*4)+(5*2)+(4*6)+(3*4)+(2*4)+(1*3)=170
170 % 10 = 0
So 1384264-43-0 is a valid CAS Registry Number.
1384264-43-0Relevant articles and documents
Synthesis method of 1-(5-chloro-3-fluoropyridine-2-yl) ethylamine
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Paragraph 0073-0079, (2020/12/30)
The invention provides a synthesis method of 1-(5-chloro-3-fluoropyridine-2-yl) ethylamine, which relates to the field of organic intermediate synthesis and comprises the following steps: 1) generating 2-(1-ethoxy vinyl)-3-fluoro-5-chloropyridine from 2-bromo-3-fluoro-5-chloropyridine and tributyl-(1-ethoxy ethylene) tin under the catalysis of tetrakis (triphenylphosphine) palladium; 2) reacting the product obtained in the step 1) with hydrochloric acid to generate 2-acetyl-3-fluorine-5-chloropyridine; 3) reducing the product obtained in the step (2) to obtain 1-(3-fluoro-5-chloropyridine-2-yl) ethane-1-ol; 4) chlorinating the product obtained in the step (3) to obtain 5-chloro-2-(1-chloroethyl)-3-fluoropyridine; 5) reacting the product obtained in the step 4) with ammonia water to obtainthe product 1-(5-chloro-3-fluoropyridine-2-yl) ethylamine. The invention has the advantages of easily available raw materials, mild reaction conditions, high selectivity, good operability of post-treatment, high yield and easiness in large-scale production.
