1384270-52-3Relevant academic research and scientific papers
High-efficiency Golgi apparatus targeting compound and biological application thereof
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Paragraph 0049-0050; 0052, (2021/11/26)
The invention discloses a high-efficiency Golgi apparatus targeting compound and biological application thereof, and the compound has the following general formula structure, wherein R1 represents an electron withdrawing group selected from one or more of electron withdrawing groups, R2 represents a substituted/substituted electron donating group in which one or multiple sites of one or more benzene rings is/are substituted by H or R3, R3 represents C1-C12 alkyl, C1-C12 alkoxy or C1-C12 fluoroalkoxy, and when the the sites are substituted by a plurality of R3 , the substituent groups are the same or different. The compound based on aggregation-induced emission can effectively target Golgi apparatus, is used for tumor treatment or cell imaging, and is especially used for cell/tissue/living tumor treatment.
