138434-80-7

Usage

Molecular structure

The compound consists of a piperidinecarboxylic acid group, four 4-(4-chlorobutoxy)-3,5-dimethoxyphenyl groups, and a 1,1-dimethylethyl ester group.

Biological activity

Piperidinecarboxylic acid derivatives are known to exhibit various biological activities, such as antiviral, antibacterial, and antifungal properties.

Lipophilic properties

The presence of multiple aromatic and alkyl groups in the molecule suggests that it may have lipophilic properties, which can affect its solubility and interaction with biological membranes.

Potential pharmaceutical applications

Due to its biological activities and lipophilic properties, the compound may be useful in drug delivery and formulation.

Further research needed

The specific properties and uses of 1-Piperidinecarboxylic acid, 4,4-bis[4-(4-chlorobutoxy)-3,5-dimethoxyphenyl]-, 1,1-dimethylethyl ester would need to be determined through additional research and testing to fully understand its potential applications and limitations.

Upstream product

• 157108-73-1 2,2'6,6'-tetramethoxy-4,4'-(piperidine-4,4-diyl)bis(phenol) 
• 134594-67-5 1-[4,4-bis(4-hydroxy-3,5-dimethoxyphenyl)piperidin-1-yl]ethan-1-one 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant academic research and scientific papers

76. Large Water-Soluble Cyclophanes with Convergent Intracavity Functionality

New tricyclic spacers, readily available trough fourfold Mannich reaction of substituted dibenzyl ketones, were introduced into a series of ten H2O-soluble cyclophanes with spacious preorganized cavity binding sites.These spacers provide H2O-solubility with amine or crown-ether functionality remote from the cyclophane cavity while directing functional groups such as keto or OH groups in a precise geometrical array inside the cavity.The cyclophanes were designed to include organic substrates via a combination of apolar and specific polar functionalgroup interactions.The X-ray crystal-structure analysis of the tritopic receptor 18 with one potential neutralmolecule and two cation-binding sites showed a large rectangular open cavity with dimensions of roughly 9 x 14 Angstroem and a spacing of 9.7 Angstroem between the O-atoms of two convergent C=O groups.Despite the binding-site preorganization, cyclophanes incorporating two of the new spacers did not show any substrate binding in aqueous solutions.The failure of these systems to function as receptors is mainly due to steric hindrance to important cyclophane aromatic ring-guest interactions.Also, the favorable solvation of the intracavity functionality may prevent the formation of complexes.Hybrid receptors constructed from the novel spacers and diphenylmethane units were found to bind flat aromatic substrates as well as bulky paracyclophanes.The observed large differences in stability (ΔΔGo > 2 kcal mol-1) of the complexes formed by three structurally closely related hybrid receptors with convergent C=O, OH, or CH2 groups and 6-hydroxynaphthalene-2-carbonitrile as guest can be explained by a strong solvation effect of the convergent functional groups on apolar inclusion complexation.