138435-64-0

Upstream product

• 500-99-2 3,5-dimethoxyphenol 
• 20717-79-7 1-bromo-2-naphthoic acid 
• 3378-82-3 1-bromo-2-naphthaldehyde 
• 117582-62-4 1-bromo-2-formyl-3,4-dihydronaphthalene 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 

Downstream Products

• 140834-50-0 (rac)-2-hydroxymethyl-(2',4'-dimethoxy-6'-hydroxyphenyl)-naphthalene 
• 142503-17-1 1-(4',6'-dimethoxy-2'-hydroxyphenyl)naphthalene-2-carbaldehyde 

Relevant academic research and scientific papers

Ruthenium-Catalyzed Atropoenantioselective Synthesis of Axial Biaryls via Reductive Amination and Dynamic Kinetic Resolution

The unprecedented ruthenium-catalyzed atropoenantioselective reductive amination of aldehydes with alkylamines via a cascade transfer hydrogenation and dynamic kinetic resolution strategy is described. This protocol features broad substrate scope and good functional group tolerance and allows the rapid assembly of axially chiral biaryls in good to high yields with high to excellent enantioselectivities. In addition, such structural motifs may have potential applications in enantioselective catalysis as chiral ligands or catalysts.

Novel Concepts in Directed Biaryl Synthesis IX. Synthesis and Structure of Benzonaphthopyranones, Useful Bridged Model Precursors for Stereoselective Biaryl Syntheses

A practicable two-step procedure for the preparation of a series of lactone-type bridged biaryls 7 as favorable substrates for subsequent atropisomer-selective ring-opening reactions is described.Due to the efficiency of the coupling step, which tolerates