1384431-89-3Relevant academic research and scientific papers
Beta-carboline alkaloids derived from the ascidian Synoicum sp.
Won, Tae Hyung,Jeon, Ju-Eun,Lee, So-Hyoung,Rho, Boon Jo,Oh, Ki-Bong,Shin, Jongheon
, p. 4082 - 4087 (2012/09/21)
Six β-carboline alkaloids (1-6) of the eudistomin Y class were isolated from the Korean ascidian Synoicum sp. These compounds were chemically converted to a known compound, eudistomin Y1 (7) and six new derivatives, designated eudistomins Y8-Y13 (8-13). Several of these natural and synthetic compounds exhibited moderate to significant antimicrobial activity, weak cytotoxic activity, and inhibitory activities toward sortase A, isocitrate lyase, and Na+/K+-ATPase. Structure-activity relationships were also deduced.
