1384442-33-4Relevant articles and documents
Primary 1,2-diamine catalysis (V): Efficient asymmetric aldol reactions of isatins with cyclohexanone
Liu, Yi,Gao, Pengchao,Wang, Junfeng,Sun, Qi,Ge, Zemei,Li, Runtao
, p. 1031 - 1034 (2012)
1,2-Diaminocyclohexane-hexanedioic acid has been demonstrated to catalyze the asymmetric aldol reactions of cycloketones and various isatin derivatives efficiently in MeOH-H. The corresponding products were obtained in good yields (70-90%) with high diastereoselectivity (up to 99:1 anti/syn) and enantioselectivity (up to 99% ee). Georg Thieme Verlag Stuttgart · New York.