1384520-22-2Relevant academic research and scientific papers
A novel strategy for the synthesis of 3-(N-heteryl)pyrrole derivatives
Khlebnikov, Alexander F.,Golovkina, Maria V.,Novikov, Mikhail S.,Yufit, Dmitry S.
, p. 3768 - 3771 (2012/08/28)
A flexible approach to unknown 1-(1H-pyrrol-3-yl)pyridinium salts with selective control of the substitution patterns, by the reaction of pyridinium ylides with 2H-azirines, is disclosed. 3-(Pyridinium-1-yl)pyrrolides, a new type of stable ylide, were prepared from these salts in high yields by treatment with base. Atmospheric-pressure hydrogenation of the ylides with Adams' catalyst lead to 1-(pyrrol-3-yl)piperidines in good yields.
