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Gurmarin, a peptide molecule derived from the Gymnema sylvestre plant, is renowned as the "sugar destroyer" or "sugar blocker" due to its capacity to diminish sugar cravings and regulate blood sugar levels. It functions by binding to taste receptors on the tongue, thereby inhibiting the sensation of sweetness and reducing the appetite for sugary foods. Furthermore, gurmarin has been observed to stimulate insulin release, enhance glucose uptake in cells, and decrease glucose absorption in the intestines, positioning it as a potential natural remedy for diabetes and obesity. Its anti-inflammatory, anti-microbial, and anti-hyperglycemic properties also render it a promising candidate for further research and medicinal applications.

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  • 138464-10-5 Structure
  • Basic information

    1. Product Name: gurmarin
    2. Synonyms: gurmarin
    3. CAS NO:138464-10-5
    4. Molecular Formula:
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 138464-10-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: gurmarin(CAS DataBase Reference)
    10. NIST Chemistry Reference: gurmarin(138464-10-5)
    11. EPA Substance Registry System: gurmarin(138464-10-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 138464-10-5(Hazardous Substances Data)

138464-10-5 Usage

Uses

Used in Diabetes Management:
Gurmarin is used as a natural treatment for diabetes due to its ability to stimulate insulin release from the pancreas, improve glucose uptake in cells, and decrease glucose absorption in the intestines. This helps in regulating blood sugar levels and managing diabetes effectively.
Used in Obesity Management:
Gurmarin is used as an appetite suppressant for obesity management, as it inhibits the ability to taste sweetness, thereby reducing the desire for sugary foods and potentially aiding in weight loss.
Used in Pharmaceutical Industry:
Gurmarin is used as a potential medicinal compound in the pharmaceutical industry for its anti-inflammatory, anti-microbial, and anti-hyperglycemic properties, making it a candidate for the development of new drugs to treat various conditions.
Used in Food Industry:
Gurmarin is used as a natural sweetener blocker in the food industry, helping to reduce sugar cravings and promote healthier food choices, which can contribute to weight management and diabetes prevention.

Check Digit Verification of cas no

The CAS Registry Mumber 138464-10-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,4,6 and 4 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 138464-10:
(8*1)+(7*3)+(6*8)+(5*4)+(4*6)+(3*4)+(2*1)+(1*0)=135
135 % 10 = 5
So 138464-10-5 is a valid CAS Registry Number.

138464-10-5Upstream product

138464-10-5Downstream Products

138464-10-5Related news

gurmarin (cas 138464-10-5) sensitivity of sweet taste responses is associated with co-expression patterns of T1r2, T1r3, and gustducin08/26/2019

Gurmarin (Gur) is a peptide that selectively suppresses sweet taste responses in rodents. The inhibitory effect of Gur differs among tongue regions and mouse strains. Recent studies demonstrated that co-expression levels of genes controlling sweet receptors (T1r2/T1r3 heterodimer) versus Gα-pro...detailed

Electrophysiological characterization of the inhibitory effect of a novel peptide gurmarin (cas 138464-10-5) on the sweet taste response in rats08/25/2019

The effect of an anti-sweet peptide, gurmarin purified from the leaves of Gymnema sylvestre, was studied electrophysiologically on taste responses of the rat chorda tympani. The action of gurmarin was highly specific to sweet taste so that responses to various sweeteners including sugars, sweet ...detailed

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