1384683-87-7Relevant academic research and scientific papers
Access to 18F-labelled isoxazoles by ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18F]fluoro-N-hydroxybenzimidoyl chloride with alkynes
Roscales, Silvia,Kniess, Torsten
, p. 393 - 403 (2019/02/13)
4-[18F]Fluoro-N-hydroxybenzimidoyl chloride (18FBIC), an 18F-labelled aromatic nitrile oxide, was developed as building block for Ru-promoted 1,3-dipolar cycloaddition with alkynes. 18FBIC is obtained in a one-p
Beyond azide-alkyne click reaction: Easy access to 18F-labelled compounds via nitrile oxide cycloadditions
Zlatopolskiy, Boris D.,Kandler, Rene,Kobus, Diana,Mottaghy, Felix M.,Neumaier, Bernd
, p. 7134 - 7136 (2012/07/27)
Radiofluorinated 4-fluorobenzonitrile oxide and N-hydroxy-4- fluorobenzimidoyl chloride rapidly react with different alkenes and alkynes under mild conditions. These cycloadditions are suitable for the preparation of low-molecular weight radiopharmaceutic
