1384848-72-9Relevant academic research and scientific papers
Regioselective synthesis of polysubstituted N 2-alkyl/aryl-1,2,3-triazoles via 4-bromo-5-iodo-1,2,3-triazole
Zhang, Li,Li, Zhibin,Wang, Xiao-Jun,Yee, Nathan,Senanayake, Chris H.
supporting information; experimental part, p. 1052 - 1056 (2012/06/04)
The regioselective N2-substitution of 4-bromo-5-iodo-1,2,3-triazole with alkyl/aryl halides in the presence of KOin DMF produced the desired 2-substituted 4-bromo-5-iodo-1,2,3-triazoles as a major products in good to excellent regioselectivity. Subsequent chemoselective Suzuki-Miyaura cross-coupling reaction of N2-substituted 4-bromo-5-iodo-1,2,3-triazoles provided polysubstituted 1,2,3-triazoles efficiently. Georg Thieme Verlag Stuttgart · New York.
