138485-44-6

Basic information

• Product Name: ethyl 4-hydroxy-2-methyl-6-oxo-5-phenyl-1-propyl-1,6-dihydro-3-pyridinecarboxylate
• Synonyms: ethyl 4-hydroxy-2-methyl-6-oxo-5-phenyl-1-propyl-1,6-dihydro-3-pyridinecarboxylate
• CAS NO: 138485-44-6
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.36364
• Mol File: 138485-44-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 4-hydroxy-2-methyl-6-oxo-5-phenyl-1-propyl-1,6-dihydro-3-pyridinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-hydroxy-2-methyl-6-oxo-5-phenyl-1-propyl-1,6-dihydro-3-pyridinecarboxylate(138485-44-6)
• EPA Substance Registry System: ethyl 4-hydroxy-2-methyl-6-oxo-5-phenyl-1-propyl-1,6-dihydro-3-pyridinecarboxylate(138485-44-6)

Safety Data

• Hazardous Substances Data: 138485-44-6(Hazardous Substances Data)

Upstream product

• 15781-73-4 di(2,4,6-trichlorophenyl)-2-phenylmalonate 
• 28043-72-3 cis-n-Propylamino-3-buten-2-carbonsaeure-aethylester 

Downstream Products

• 138485-52-6 4-Hydroxy-2-methyl-6-oxo-5-phenyl-1-propyl-1,6-dihydro-pyridine-3-carboxylic acid 
• 138485-70-8 4-Hydroxy-6-methyl-3-phenyl-1-propyl-1H-pyridin-2-one 

Relevant articles and documents

Anti-mycobacterial 4-hydroxy-3-phenylpyridin-2(1H)-ones

4-Hydroxy-3-phenylpyridin-2 (1H)-ones with different substituents either at N-1 or in the phenyl group were synthesized by reaction of ethyl β-aminocrotonates with dialkyl malonates or 'magic malonates' (2,4,6-trichlorophenyl malonates).The evaluation of these compounds on Mycobacterium tuberculosis H37Ra, Escherichia coli B and Staphylococcus aureus ATCC 25923 showed significant inhibitory effects on M tuberculosis (5g and 5s, MIC=8μg/ml).A structure-activity relationship is discussed.