138494-50-5

Basic information

• Product Name: 7,9-Dimethyl-4-oxo-3-phenyl-2-thioxo-3,4-dihydro-2H-[1,3]thiazino[6,5-b]indolizine-10-carboxylic acid ethyl ester
• CAS NO: 138494-50-5
• Molecular Weight: 410.518
• Mol File: 138494-50-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7,9-Dimethyl-4-oxo-3-phenyl-2-thioxo-3,4-dihydro-2H-[1,3]thiazino[6,5-b]indolizine-10-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7,9-Dimethyl-4-oxo-3-phenyl-2-thioxo-3,4-dihydro-2H-[1,3]thiazino[6,5-b]indolizine-10-carboxylic acid ethyl ester(138494-50-5)
• EPA Substance Registry System: 7,9-Dimethyl-4-oxo-3-phenyl-2-thioxo-3,4-dihydro-2H-[1,3]thiazino[6,5-b]indolizine-10-carboxylic acid ethyl ester(138494-50-5)

Safety Data

• Hazardous Substances Data: 138494-50-5(Hazardous Substances Data)

Upstream product

• 129169-99-9 2-(2-Ethoxycarbonyl-ethylsulfanyl)-6,8-dimethyl-indolizine-1,3-dicarboxylic acid diethyl ester 
• 103-72-0 phenyl isothiocyanate 

Relevant articles and documents

Preparation of New Nitrogen-Bridged Heterocycles. 27. First Synthesis of 1,3-Thiazinoindolizine Derivatives

Potassium 2-indolizinethiolates, generated in situ from the treatment of dialkyl 2-indolizine-1,3-dicarboxylates with potassium t-butoxide in N,N-dimethylformamide, reacted smoothly with various isothiocyanates and isocyanates with the elimination of alkoxide ions to give new heterocyclic compounds, alkyl 4(3H)-oxo-2-thioxo- and 2,4(3H)-dioxo-2H-1,3-thiazinoindolizine-10-carboxylates, in moderate to good yields.The structures of these 1,3-thiazinoindolizine derivatives were determined mainly by elemental analyses and spectral inspections, and the structural assignment was finally confirmed by the single crystal X-ray analyses of two compounds.