1384975-91-0Relevant academic research and scientific papers
Synthesis of naphtho[2,1-b[pyrano pyrrolothiazole derivatives through 1,3-cycloaddition reaction
Kathiravan, Subban,Raghunathan, Raghavachary
, p. 3068 - 3076 (2012)
Facile synthesis of a series of naphtho[2,1,b]pyrano pyrrolo thiazoles was accomplished in good yields in a one-pot reaction through intramolecular 1,3-dipolar cycloaddition of cyclic azomethine ylides with Baylis-Hillman adducts as dipolarophiles. The protocol is applicable to a wide variety of photochromic and biologically active napthopyrano products. The regio-and stereochemical outcome of the cycloaddition reaction was ascertained by X-ray crystallographic study of one of the cycloadducts.
