1384983-89-4Relevant academic research and scientific papers
Aryl nitrile oxide cycloaddition reactions in the presence of pinacol boronic acid ester
Harding, Sarah L.,Marcuccio, Sebastian M.,Savage, G. Paul
, p. 606 - 612 (2012/06/01)
An aryl substrate with dual functionality consisting of a nitrile oxide and a pinacolyl boronate ester was prepared by mild hypervalent iodine oxidation (diacetoxyiodobenzene) of the corresponding aldoxime, without decomposition of the boronate functionality. The nitrile oxide was trapped in situ with a variety of dipolarophiles to yield aryl isoxazolines with the boronate ester function intact and available for subsequent reaction.
