1384987-36-3Relevant academic research and scientific papers
N-heterocyclic carbene catalyzed intramolecular hydroacylation of alkynylphosphonates
Wang, Zhenqiang,Yu, Zhihua,Wang, Ying,Shi, Deqing
, p. 1559 - 1568 (2012/06/18)
Two exocyclic and endocyclic olefin tautomers of chromone phosphonates were obtained in good to excellent yields at different temperatures by utilizing an N-heterocyclic carbene catalyst in the intramolecular reactions between the formyl group and alkynylphosphonates. The exocyclic olefins can isomerize to the endocyclic derivatives completely when treated with a thiazolium salt precatalyst and potassium carbonate at 30C for three to fivehours. In addition, the chromone phosphonate derivatives were also applied in the one-pot synthesis of benzopyranopyridine phosphonates in moderated yields.
