138499-82-8Relevant academic research and scientific papers
An efficient microwave-promoted route to (Z)-stilbenes from trans-cinnamic acids: Synthesis of combretastatin A-4 and analogues
Bazin, Marc-Antoine,Jouanne, Marie,El-Kashef, Hussein,Rault, Sylvain
, p. 2789 - 2794 (2009)
cis-Stilbenes were synthesized from trans-cinnamic acids, involving ethylenic-bond bromination and a subsequent one-pot microwave-promoted stereoselective debrominative decarboxylation-Suzuki cross-coupling strategy. This sequence represents a useful way to prepare a variety of combretastatin A-4 derivatives.
