1385023-77-7Relevant academic research and scientific papers
Palladium-catalyzed cross-coupling of various phosphorus pronucleophiles with chloropyrazines: Synthesis of novel Am(iii)-selective extractants
Nikishkin, Nicolai I.,Huskens, Jurriaan,Assenmacher, Jana,Wilden, Andreas,Modolo, Giuseppe,Verboom, Willem
, p. 5443 - 5451 (2012/07/30)
Palladium-catalyzed cross-coupling of (di)chloropyrazines with phosphorus pronucleophiles in the presence of a base gave the phosphorylated pyrazines in 81-95% yields. Based on this methodology a series of appropriately functionalized pyrazines was prepared as potential extractants of trivalent cations from highly acidic nuclear waste. A few hydrophilic derivatives exhibited a very good selectivity for Am3+ over Eu3+ with separation factors up to 40 at pH 1 at 0.01 mol L-1 ligand concentration.
