1385043-49-1

Basic information

• Product Name: 1-(3-methoxy-1-trifluoromethanesulfonyl-1,2-dihydropyrazin-2-yl)cyclohexane-1-carboxylic acid
• CAS NO: 1385043-49-1
• Molecular Weight: 370.35
• Mol File: 1385043-49-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-methoxy-1-trifluoromethanesulfonyl-1,2-dihydropyrazin-2-yl)cyclohexane-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-methoxy-1-trifluoromethanesulfonyl-1,2-dihydropyrazin-2-yl)cyclohexane-1-carboxylic acid(1385043-49-1)
• EPA Substance Registry System: 1-(3-methoxy-1-trifluoromethanesulfonyl-1,2-dihydropyrazin-2-yl)cyclohexane-1-carboxylic acid(1385043-49-1)

Safety Data

• Hazardous Substances Data: 1385043-49-1(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 40348-04-7 (Bis-trimethylsilanyloxy-methylene)-cyclohexane 
• 3149-28-8 2-methoxypyrazine 

Relevant articles and documents

Synthesis of new γ-lactones from preactivated monosubstituted pyrazines and TMS-ketene acetals

The double addition of bis(trimethylsilyl) ketene acetals (1a-1b, R 1 = CH3,-(CH2)5-) to 2-substituted pyrazines promoted by triflic anhydride leads to γ-lactones in a single step. A systematic study involving electron-withdrawing and electron-donating groups (R2 = CN, COOMe, PhCH=CH, Cl, Me, OMe) in the pyrazine ring reveals a strong dependence of electronic effects on the regiochemistry of nucleophilic addition.