1385059-48-2Relevant articles and documents
On water direct Pd-catalysed C-H arylation of thiazolo[5,4-d]pyrimidine derivatives
Su, Ye-Xiang,Deng, Ya-Hui,Ma, Ting-Ting,Li, Yu-Yan,Sun, Li-Ping
, p. 1979 - 1981 (2012/08/14)
A novel protocol for the direct arylation of thiazolo[5,4-d]pyrimidine derivatives with aryl iodides is reported. The reactions were catalysed by a combination of Pd(PPh3)4 and Ag2CO3 (acting as the oxidant and the base as well), using exclusively water as the solvent and furnishing the desired products in good to excellent yields at only 60 °C. The Royal Society of Chemistry 2012.