1385064-70-9Relevant articles and documents
Hetero-Diels-Alder reaction of photochemically generated α-hydroxy-o-quinodimethanes with trifluoromethyl ketones
Takaki, Ken,Fujii, Toshifumi,Yonemitsu, Hosei,Fujiwara, Makoto,Komeyama, Kimihiro,Yoshida, Hiroto
supporting information; experimental part, p. 3974 - 3976 (2012/09/08)
Hetero-Diels-Alder reaction of α-hydroxy-o-quinodimethanes photochemically generated from o-tolualdehydes with trifluoromethyl ketones gave a mixture of hemiacetals and hydroxyaldehydes in fairly good yields. Their subsequent oxidation with PCC provided 1-isochromanones as formal oxidative [4+2] cycloaddition products. In contrast, similar reaction of aromatic ketones such as o-methylbenzophenone, 1-indanone, and α-tetralone gave exclusively the corresponding ketones having (trifluoromethyl)methylol groups at the o-position.