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1385068-20-1

(E)-(S)-4-[(R)-1-hydroxy-2-(3-isopropyl-benzylamino)-ethyl]-16-methyl-6-oxa-3,12-diaza-bicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1385068-20-1 Structure

  • Basic information

    1. Product Name: (E)-(S)-4-[(R)-1-hydroxy-2-(3-isopropyl-benzylamino)-ethyl]-16-methyl-6-oxa-3,12-diaza-bicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione
    2. Synonyms: (E)-(S)-4-[(R)-1-hydroxy-2-(3-isopropyl-benzylamino)-ethyl]-16-methyl-6-oxa-3,12-diaza-bicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione
    3. CAS NO:1385068-20-1
    4. Molecular Formula:
    5. Molecular Weight: 479.619
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1385068-20-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (E)-(S)-4-[(R)-1-hydroxy-2-(3-isopropyl-benzylamino)-ethyl]-16-methyl-6-oxa-3,12-diaza-bicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E)-(S)-4-[(R)-1-hydroxy-2-(3-isopropyl-benzylamino)-ethyl]-16-methyl-6-oxa-3,12-diaza-bicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione(1385068-20-1)
    11. EPA Substance Registry System: (E)-(S)-4-[(R)-1-hydroxy-2-(3-isopropyl-benzylamino)-ethyl]-16-methyl-6-oxa-3,12-diaza-bicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione(1385068-20-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1385068-20-1(Hazardous Substances Data)

1385068-20-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1385068-20-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,5,0,6 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1385068-20:
(9*1)+(8*3)+(7*8)+(6*5)+(5*0)+(4*6)+(3*8)+(2*2)+(1*0)=171
171 % 10 = 1
So 1385068-20-1 is a valid CAS Registry Number.

1385068-20-1Downstream Products

1385068-20-1Relevant articles and documents

Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: Design, synthesis and X-ray crystal structures of enzyme inhibitor complexes

Sandgren, Veronica,Agback, Tatiana,Johansson, Per-Ola,Lindberg, Jimmy,Kvarnstr?m, Ingemar,Samuelsson, Bertil,Belda, Oscar,Dahlgren, Anders

, p. 4377 - 4389 (2012/08/28)

A series of P1-P3 linked macrocyclic BACE-1 inhibitors containing a hydroxyethylamine (HEA) isostere scaffold has been synthesized. All inhibitors comprise a toluene or N-phenylmethanesulfonamide P2 moiety. Excellent BACE-1 potencies, both in enzymatic an

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