1385183-75-4Relevant academic research and scientific papers
Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles
Mandadapu, Sivakoteswara Rao,Weerawarna, Pathum M.,Gunnam, Mallikarjuna Reddy,Alliston, Kevin R.,Lushington, Gerald H.,Kim, Yunjeong,Chang, Kyeong-Ok,Groutas, William C.
scheme or table, p. 4820 - 4826 (2012/08/07)
Series of structurally-diverse α-ketoamides and α- ketoheterocycles was synthesized and subsequently investigated for inhibitory activity against Norwalk virus 3C protease in vitro, as well as anti-norovirus activity in a cell-based replicon system.
