138535-54-3Relevant academic research and scientific papers
Development of chiral stabilised azomethine ylids: A chiral memory relay system
Anslow,Harwood,Phillips,Watkin,Wong
, p. 1343 - 1358 (2007/10/02)
Chiral, stabilised azomethine ylids incorporated in cyclic templates derived from (R)- or (S)-2-phenylglycinol and (S)-valine undergo enantioselective 1,3-dipolar cycloaddition reactions with a variety of dipolarophiles. Removal of the template in the cas
Development of chiral stabilised azomethine ylids: Completing the memory relay
Anslow,Harwood,Phillips,Watkin
, p. 997 - 1000 (2007/10/02)
We report how the α-chirality of L-valine can be 'memorised' through a sequence involving chirality transfer to a cyclic template, followed by azomethine ylid generation and enantiospecific cycloaddition to regenerate the centre lost during ylid formation
