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138544-91-9

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138544-91-9 Usage

Description

9-hydroxycanthin-6-one is an indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 9. It is isolated from the roots of Eurycoma longifolia and exhibits antineoplastic activity.

Uses

Used in Pharmaceutical Industry:
9-hydroxycanthin-6-one is used as an antineoplastic agent for its ability to inhibit the growth and progression of cancer cells. It is particularly effective against various types of solid malignancies, making it a promising candidate for cancer treatment.
Used in Drug Development:
9-hydroxycanthin-6-one is used as a key compound in the development of novel drug delivery systems. These systems aim to enhance the bioavailability, delivery, and therapeutic outcomes of the compound, potentially improving its efficacy against cancer cells and overcoming limitations associated with its use.
Used in Cancer Research:
9-hydroxycanthin-6-one serves as a valuable tool in cancer research, providing insights into the mechanisms of cancer cell growth and progression. Its antineoplastic properties make it an important subject of study for the development of new cancer treatments and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 138544-91-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,4 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 138544-91:
(8*1)+(7*3)+(6*8)+(5*5)+(4*4)+(3*4)+(2*9)+(1*1)=149
149 % 10 = 9
So 138544-91-9 is a valid CAS Registry Number.

138544-91-9Upstream product

138544-91-9Downstream Products

138544-91-9Related news

9-Hydroxycanthin-6-one (cas 138544-91-9) isolated from stem bark of Ailanthus altissima induces ovarian cancer cell apoptosis and inhibits the activation of tumor-associated macrophages08/24/2019

The stem bark of Ailanthus altissima is used in traditional medicine in Asia to treat a variety of diseases, including cancer. The aim of this study was to identify compounds with tumoricidal activity from A. altissima stem bark and to investigate their mechanisms of action. Among the 13 compoun...detailed

138544-91-9Relevant articles and documents

Canthin-6-one and β-carboline alkaloids from Eurycoma harmandiana

Kanchanapoom, Tripetch,Kasai, Ryoji,Chumsri, Phannipha,Hiraga, Yoshikazu,Yamasaki, Kazuo

, p. 383 - 386 (2007/10/03)

Two alkaloids, canthin-6-one 9-O-β-glucopyranoside and 7-hydroxy-β-carboline 1-propionic acid, were isolated from the roots of Eurycoma harmandiana, together with the five known canthin-6-one alkaloids, 9-hydroxycanthin-6-one, 9-methoxycanthin-6-one, 9.10-dimethoxycanthin-6-one, canthin-6-one and canthin-6-one N-oxide, and the two known β-carboline alkaloids, β-carboline 1-propionic acid and 7-methoxy-β-carboline 1-propionic acid. Their structures were based on analyses of spectroscopic data.

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