138573-34-9

Upstream product

• 111604-85-4 [2-(5-trifluoromethyl-2-nitrophenyl)-1-(4-methoxyphenyl)ethyl]propanedioic acid,dimethyl ester 

Downstream Products

• 138573-46-3 2-[2-(2-Amino-5-trifluoromethyl-phenyl)-1-(4-methoxy-phenyl)-ethyl]-2-propyl-malonic acid dimethyl ester 
• 111604-71-8 (3R,4S)-1-(2-Dimethylamino-ethyl)-4-(4-methoxy-phenyl)-3-propyl-7-trifluoromethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one 
• 111604-71-8 (3S,4S)-1-(2-Dimethylamino-ethyl)-4-(4-methoxy-phenyl)-3-propyl-7-trifluoromethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one 
• 138573-60-1 (3S,4R)-4-(4-Methoxy-phenyl)-2-oxo-3-propyl-7-trifluoromethyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-3-carboxylic acid methyl ester 
• 111604-98-9 1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-3-propyl-7-(trifluoromethyl)-2H-1-benzazepin-2-one 

Relevant academic research and scientific papers

Benzazepinone Calcium Channel Blockers. 3. Synthesis and Structure-Activity Studies of 3-Alkylbenzazepinones

As part of a program aimed at identifying novel analogues of diltiazem, we developed several synthetic routes for 3-alkylbenzazepinones, both in racemic and nonracemic form.Structure-activity relationship studies in this series have led to identification