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GALANTIDE is a synthetic peptide that functions as a potent and selective antagonist of the human galanin receptor subtype GALR2. Galanin, a neuropeptide, is involved in the regulation of various physiological processes such as pain perception, stress response, and feeding behavior. GALANTIDE is utilized in research to investigate the role of galanin signaling in different disease conditions, including neuropathic pain and depression. Its capacity to inhibit GALR2 activity renders it a valuable research tool for understanding the function of galanin receptors and exploring the therapeutic potential of modulating their activity.

138579-66-5

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138579-66-5 Usage

Uses

Used in Pharmaceutical Research:
GALANTIDE is used as a research tool for studying the role of galanin signaling in various disease states, particularly neuropathic pain and depression. Its ability to block GALR2 activity aids in understanding the receptor's function and the potential therapeutic applications of modulating its activity.
Used in Drug Development:
GALANTIDE is used as a lead compound in the development of drugs targeting the galanin receptor GALR2. By inhibiting the receptor, GALANTIDE may contribute to the discovery of new therapeutic agents for the treatment of pain, stress-related disorders, and eating disorders.
Used in Neuroscience:
In the field of neuroscience, GALANTIDE is used as a selective antagonist to explore the mechanisms of galanin receptor signaling in the central nervous system. This helps researchers to better understand the role of galanin in cognitive functions, mood regulation, and other neurological processes.
Used in Preclinical Studies:
GALANTIDE is used in preclinical studies to evaluate the efficacy and safety of galanin receptor antagonists as potential therapeutic agents. These studies provide valuable insights into the pharmacological properties of GALANTIDE and its potential use in clinical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 138579-66-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,7 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 138579-66:
(8*1)+(7*3)+(6*8)+(5*5)+(4*7)+(3*9)+(2*6)+(1*6)=175
175 % 10 = 5
So 138579-66-5 is a valid CAS Registry Number.
InChI:InChI=1/C104H151N25O26S/c1-54(2)39-70(91(142)113-52-87(139)129-37-20-27-80(129)103(154)120-69(33-35-82(107)134)93(144)119-68(32-34-81(106)133)94(145)124-76(44-61-23-16-13-17-24-61)99(150)123-74(43-60-21-14-12-15-22-60)92(143)112-51-86(138)116-71(40-55(3)4)95(146)118-67(89(109)140)36-38-156-11)121-96(147)72(41-56(5)6)122-98(149)75(45-62-28-30-64(132)31-29-62)117-85(137)50-111-90(141)58(9)114-102(153)79(53-130)127-100(151)78(47-83(108)135)125-97(148)73(42-57(7)8)126-104(155)88(59(10)131)128-101(152)77(115-84(136)48-105)46-63-49-110-66-26-19-18-25-65(63)66/h12-19,21-26,28-31,49,54-59,67-80,88,110,130-132H,20,27,32-48,50-53,105H2,1-11H3,(H2,106,133)(H2,107,134)(H2,108,135)(H2,109,140)(H,111,141)(H,112,143)(H,113,142)(H,114,153)(H,115,136)(H,116,138)(H,117,137)(H,118,146)(H,119,144)(H,120,154)(H,121,147)(H,122,149)(H,123,150)(H,124,145)(H,125,148)(H,126,155)(H,127,151)(H,128,152)/t58-,59+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,88-/m0/s1

138579-66-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Galantide

1.2 Other means of identification

Product number -
Other names M15

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138579-66-5 SDS

138579-66-5Upstream product

138579-66-5Downstream Products

138579-66-5Related news

The efficacy of combining feG and GALANTIDE (cas 138579-66-5) in mild caerulein-induced acute pancreatitis in mice09/04/2019

We have previously shown that galantide ameliorates mild acute pancreatitis (AP), and the salivary tripeptide analogue, feG, ameliorates severe AP in mice. In this study, we compared the efficacy of combining galantide and feG with that of the individual agents in treating mild AP induced in mic...detailed

Original ArticlesOctreotide negates the benefit of GALANTIDE (cas 138579-66-5) when used in the treatment of caerulein-induced acute pancreatitis in mice09/03/2019

BackgroundWe have previously shown that galantide, a non-specific galanin receptor antagonist, ameliorates acute pancreatitis (AP) induced in mice. Octreotide, a somatostatin analogue, has been used in the treatment of AP with inconsistent outcomes. This study set out to compare the efficacy of ...detailed

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