138580-53-7Relevant academic research and scientific papers
DIASTEROSELCTIVITY IN THE REACTION OF 3-METHYL-5-(METHYL- OT PHENYL)ISOXAZOL-4-YLLITHIUM AND α,α'-DIMETHYLCYCLOALKANONES
Polo, Cecilia,Ramos, Vicente,Torroba, Tomas,Rodrigues, Matias L.,Bossio, Ricardo,et al.
, p. 1757 - 1764 (2007/10/02)
Addition of 3-methyl-4-lithio-5-(methyl- or phenyl)isoxazoles to stereoisomeric mixtures of α,α'-dimethylcycloalkanones afforded meso 1S*,2R*,(5 or 6)S*-2,(5 or 6)-dimethyl-1-cycloalkan-1-ols.In one case none of meso form, but only the racemic 2,6-dimethyl-1-(3'-methyl-5'-phenylisoxazol-4'-yl)cyclohexan-1-ol was obtained.This compound showed restricted rotation phenomena at room tempertaure.
