1385860-98-9

Basic information

• Product Name: 1-[3-(4-chlorophenyl)acryloyl]-3,5-dimethyl-1H-pyrazole
• Synonyms: 1-[3-(4-chlorophenyl)acryloyl]-3,5-dimethyl-1H-pyrazole
• CAS NO: 1385860-98-9
• Molecular Formula: C14H13ClN2O
• Molecular Weight: 260.71882
• Mol File: 1385860-98-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[3-(4-chlorophenyl)acryloyl]-3,5-dimethyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(4-chlorophenyl)acryloyl]-3,5-dimethyl-1H-pyrazole(1385860-98-9)
• EPA Substance Registry System: 1-[3-(4-chlorophenyl)acryloyl]-3,5-dimethyl-1H-pyrazole(1385860-98-9)

Safety Data

• Hazardous Substances Data: 1385860-98-9(Hazardous Substances Data)

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 1615-02-7 p-chlorocinnamic acid 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1623808-11-6 C₁₅H₁₄ClN₃O 

Relevant articles and documents

Enantioselective Synthesis of N?H-Free 1,5-Benzothiazepines

An enantioselective sulfa-Michael-cyclization reaction was developed for the synthesis of 1,5-benzothiazepines with versatile pharmacological activities. The reaction between 2-aminothiophenol and α,β-unsaturated pyrazoleamides gave direct access to N?H-free 1,5-benzothiazepines in the presence of a chiral N,N′-dioxide/Yb(OTf)3complex. Excellent enantioselectivities (up to 96 % ee) and high yields (up to 99 %) were obtained for a broad range of substrates under mild reaction conditions. This method provided a facile approach to the antidepressant drug (R)-(?)-Thiazesim.