138587-54-9Relevant academic research and scientific papers
Synthesis and reactivity of alkenyl- and alkynyl-substituted β,β-dihalo-and?β,β,β-trichloroamines
Abbaspour Tehrani, Kourosch,Stas, Sara,Lucas, Bart,De Kimpe, Norbert
experimental part, p. 1957 - 1966 (2009/08/07)
β,β-Dihalo- and β,β,β-trichloroamines, obtained by Lewis acid-promoted Petasis-type reaction of α,α-dichlorinated and α,α,α-trichlorinated imines or reduction of α,α-dihaloaldimines, were subjected to a reactivity study and turned out to be remarkably sta
Easy and General Synthesis of Unsymmetrical α-Halogeno Ketones
Barluenga, Jose,Llavona, Lujan,Yus, Miguel,Concellon, Jose M.
, p. 2890 (2007/10/02)
The reaction of carboxylic acid esters 1 with in situ generated bromohalomethyllithium (1:2 molar ratio) at -78 deg C followed by reaction with lithium dialkylcuprate (1:1 molar ratio) at 0 deg C, leads, after hydrolysis, to the corresponding α-chloro or α-bromo ketones 3.
