1385878-18-1Relevant articles and documents
Enantioselective organo-SOMO cycloadditions: A catalytic approach to complex pyrrolidines from olefins and aldehydes
Jui, Nathan T.,Garber, Jeffrey A.O.,Finelli, Fernanda Gadini,MacMillan, David W.C.
, p. 11400 - 11403 (2012/09/05)
A new method to rapidly generate pyrrolidines via a SOMO-activated enantioselective (3 + 2) coupling of aldehydes and conjugated olefins has been accomplished. A radical-polar crossover mechanism is proposed wherein olefin addition to a transient enamine