138589-41-0Relevant academic research and scientific papers
An Efficient Synthesis of Heterocyclic Analogs of 1-Arylnaphthalene Lignans
Kuroda, Tooru,Takahashi, Masami,Ogiku, Tsuyoshi,Ohmizu, Hiroshi,Nishitani, Takashi,et al.
, p. 7353 - 7357 (2007/10/02)
The heterocyclic analogs 5a-f, 16, and 20 of 1-arylnaphthalene lignans were synthesized by Diels-Alder reactions of acetoxy aldehydes 11a-f, 14, and 18 with dimethyl acetylenedicarboxylate.A pathway for formation of 5a-f, 16, and 20 through the intermediacy of heteroaromatic isobenzofurans derived from acetoxy aldehydes is discussed.
