138604-23-6

Upstream product

• 29783-26-4 cis-4-cyclopentene-1,3-diol 
• 4083-64-1 Tosyl isocyanate 
• 158361-26-3 N,N′-ditosyl-meso-cyclopent-4-ene-1,3-diol biscarbamate 

Downstream Products

• 102822-56-0 mannostatin A 
• 135075-48-8 N-((3aR,4S,5R,6R,6aS)-6-Hydroxy-2,2-dimethyl-5-methylsulfanyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl)-4-methyl-benzenesulfonamide 
• 135075-50-2 N-((1aS,1bR,4aR,5R,5aS)-3,3-Dimethyl-tetrahydro-1,2,4-trioxa-cyclopropa[a]pentalen-5-yl)-4-methyl-benzenesulfonamide 
• 147695-83-8 (3aR,6S,6aR)-6-Hydroxy-3-(toluene-4-sulfonyl)-3,3a,6,6a-tetrahydro-cyclopentaoxazol-2-one 
• 135075-49-9 N-((3aR,4R,6aS)-2,2-Dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-yl)-4-methyl-benzenesulfonamide 
• 135075-46-6 N-((1R,4S,5R)-4,5-Dihydroxy-cyclopent-2-enyl)-4-methyl-benzenesulfonamide 
• 135075-44-4 (3aR,6aR)-3-(Toluene-4-sulfonyl)-3a,6a-dihydro-3H-cyclopentaoxazole-2,6-dione 

Relevant academic research and scientific papers

Diamidophosphite–oxazolines with a pyridine core in Pd-catalyzed asymmetric reactions

We have designed and synthesized a small library of readily available P,N,N-diamidophosphite–oxazoline ligands containing 1,3,2-diazaphospholidine rings and a pyridine moiety. The use of these ligands provides up to 96% ee in Pd-catalyzed asymmetric allyl

Chiral (salen)Co(III)(N-benzyl-l-serine)-derived phosphites: monodentate P-ligands for enantioselective catalytic applications

Reaction of the (S,S)-salen-cobalt(III)-N-benzyl-l-serine complex 2 with four diol-derived chlorophosphites afforded phosphites 3a-3d in moderate yields (37-72%). Structural studies of these monodentate phosphite ligands and of their Rh-complexes were per

Parallel approach to selective catalysts for palladium-catalyzed desymmetrization of 2,4-cyclopentenediol

(Matrix presented) Work toward the development of a bis-phosphine ligand system for the palladium-catalyzed desymmetrization of meso-diols is reported. A parallel approach using phosphine-containing amino acids and a "representational search" was taken to

On the source of transfer of stereochemical information in ligands for Pd-catalyzed AAA reactions

Examination of a series of ligands for a Pd-catalyzed asymmetric allylic alkylation (AAA) suggests the importance of buttressing effects for creating chiral space for high enantioselectivity.

Nonsimple relationships between the P*-chiral diamidophosphite and the arylphosphine moieties in Pd-catalyzed asymmetric reactions: Combinatorial approach and P,P*-bidentate phosphine-diamidophosphites

A small family of P,P*-bidentate C1-symmetric ligands containing 1,3,2-diazaphospholidine rings with stereogenic phosphorus atoms has been prepared. Palladium catalytic systems with these phosphine-diamidophosphites afforded 95% and

Palladium catalyzed asymmetric reactions assisted by P*,P*-bidentate bisdiamidophosphites based on 1,4-diols

A small series of P*,P*-bidentate bisdiamidophosphite ligands containing 1,3,2-diazaphospholidine rings have been prepared. The cationic [Pd(allyl)(P*,P*)]BF4and neutral [Pd(P*,P*)Cl2] palladium(II) complexes were synthesized with on

Diamidophosphites with remote P*-stereocentres and their performance in Pd-catalyzed enantioselective reactions

Diamidophosphite ligands based on 1,1′-bis(hydroxymethyl)ferrocene or N1,N2-bis((S)-1-hydroxy-3,3-dimethylbutan-2-yl)oxalamide and bearing 1,3,2-diazaphospholidine rings with stereogenic phosphorus atoms were obtained. The use of the

Application of pyranoside phosphite-pyridine ligands to enantioselective metal-catalyzed allylic substitutions and conjugate 1,4-additions

A series of glucopyranoside phosphite-pyridine ligands have been applied in the metal-catalyzed allylic substitution and conjugate 1,4-addition reactions of several substrate types. We have been able to identify ligands that provided promising enantioselectivities in the Pd-catalyzed intermolecular allylic substitution of cyclic substrates (ee's up to 86%) and desymmetrization (ee's up to 94%) and in the Cu-catalyzed conjugate addition of challenging aliphatic enones (ee's up to 90%).

Phosphites and diamidophosphites based on mono-ethers of BINOL: A comparison of enantioselectivity in asymmetric catalytic reactions

Novel P-monodentate phosphite-type ligands have been synthesized in one step from BINOL mono-tosylate and BINOL mono-(-)-menthylcarbonate. The use of these ligands provides up to 96% ee in Pd-catalyzed asymmetric allylic substitution of (E)-1,3-diphenylal

Pd-Catalyzed asymmetric transformations involving P*-mono- and P*,N-bidentate diamidophosphites derived from (2S,3S)-N 2,3-dimethyl-N 1-phenylpentane-1,2-diamine

The synthesis of new P*-mono- and P*,N-bidentate diamidophosphites, containing 1,3,2-diazaphospholidine rings formed starting from (2S,3S)-N 2,3-dimethyl-N 1-phenylpentane-1,2-diamine, is described. Comparison of their efficiency in