138608-02-3

Usage

Molecular structure

1R,2R-N,N'-bis((2,4,6-triMethylphenyl)Methyl)-1,2-diphenyl-1,2-EthanediaMine has a complex molecular structure with two chiral centers and multiple phenyl and methyl groups.

Classification

It is an organic compound and belongs to the class of ethanediamine derivatives.

Usage

Commonly used as a chiral ligand in various catalytic reactions.

Chiral centers

Characterized by its two chiral centers, which contribute to its unique properties and applications.

Coordination complexes

Ability to form coordination complexes with a variety of metal ions.

Application in asymmetric catalysis

Utilized in asymmetric catalysis, a key technique in the synthesis of chiral molecules.

Potential applications

Studied for its potential applications in the synthesis of pharmaceuticals and other important organic molecules.

Importance in organic chemistry and catalysis

Due to its unique structure and properties, 1R,2R-N,N'-bis((2,4,6-triMethylphenyl)Methyl)-1,2-diphenyl-1,2-EthanediaMine is an important entity in the fields of organic chemistry and catalysis.

Upstream product

• 487-68-3 mesytaldehyde 
• 192649-51-7 (R,R)-1,2-Ph₂-N,N'-bis(mesitylmethylidene)ethane-1,2-diamine 
• 23873-81-6 benzildioxime 
• 951-87-1 rac-1,2-diphenylethylene-1,2-diamine 
• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 124151-16-2 (1S,2S)-1,2-Diphenyl-N,N'-bis-[1-(2,4,6-trimethyl-phenyl)-meth-(Z)-ylidene]-ethane-1,2-diamine 

Downstream Products

• 162525-43-1 PtCl2(1,2-diphenyl-N,N'-bis[(2,4,6-trimethylphenyl)methyl]-1,2-diaminoethane)(η(2)-E-2-butene) 
• 162525-50-0 PtClMe(1,2-diphenyl-N,N'-bis[(2,4,6-trimethylphenyl)methyl]-1,2-diaminoethane)(η(2)-E-2-butene) 
• 162525-45-3 PtCl2(1,2-diphenyl-N,N'-bis[(2,4,6-trimethylphenyl)methyl]-1,2-diaminoethane)(η(2)-1-butene) 
• 162525-52-2 PtClMe(1,2-diphenyl-N,N'-bis[(2,4,6-trimethylphenyl)methyl]-1,2-diaminoethane)(η(2)-styrene) 
• 162525-44-2 PtCl2(1,2-diphenyl-N,N'-bis[(2,4,6-trimethylphenyl)methyl]-1,2-diaminoethane)(η(2)-propene) 

Relevant academic research and scientific papers

Zinc Acetate Catalyzed Enantioselective Reductive Aldol Reaction of Ketones

A highly enantioselective method for the synthesis of β-hydroxy esters via reductive aldol reaction of acrylates with aryl and heteroaromatic ketones is described. In situ generated catalyst composed of zinc acetate and chiral diamine afforded enantioenri

Efficient syntheses of four stable-isotope labeled (1R)-menthyl (1S,2S)-(+)-2-phenylcyclopropanecarboxylates

Many carbenoid cyclopropanation reactions promoted by chiral catalysts give product mixtures reflecting impressive diastereo- and enantioselectivities. Few provide a single chiral product efficiently. This limitation has been overcome in cyclopropanations of styrene and isotopically labeled styrenes with α-diazoacetates. Convenient syntheses on a 20 g scale of each of four chiral isotopically labeled (1R)-menthyl (1S,2S)-2- phenylcyclopropanecarboxylates (the 1-d-3-13C, 1,(3S)-d2, 1,2,(3S)-d3, and 1,3,3-d3 isotopomers) of better than 99% ee have been realized. The Royal Society of Chemistry 2006.

Organic chemistry: Preparative synthesis of the Corey chiral controller for enantioselective dihydroxylation of olefins

A five-step synthesis of both enantiomers of 1,2-di(2,4,6-trimethylbenzylamino)-1,2-diphenylethane, i.e., Corey (R,R)- and (S,S)-controllers for enantioselective dihydroxylation of olefins by osmium tetroxide, starting from α,α'-diphenylglyoxime, has been developed. The key operations in the synthesis are the optical resolution of intermediate rac-1,2-diamino-1,2-diphenylethane into two enantiomers using only (R,R)-tartaric acid and the subsequent enhancement of the enantiomeric purity to >98% by crystallizations of the corresponding Schiff's bis-bases. Analysis of the enantiomeric purity of the controllers can be easily performed using 1H NMR spectra of their salts with (R)-α-methoxy-α-(trifluoromethyl)phenylacetic acid (Mosher R-acid).