138631-10-4

Basic information

• Product Name: 1H-Tetrazole, 5-[3-[5-[4-(4-phenylbutoxy)phenyl]-2H-tetrazol-2-yl]propyl]-
• CAS NO: 138631-10-4
• Molecular Formula: C21H24N8O
• Molecular Weight: 404.475
• Mol File: 138631-10-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Tetrazole, 5-[3-[5-[4-(4-phenylbutoxy)phenyl]-2H-tetrazol-2-yl]propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole, 5-[3-[5-[4-(4-phenylbutoxy)phenyl]-2H-tetrazol-2-yl]propyl]-(138631-10-4)
• EPA Substance Registry System: 1H-Tetrazole, 5-[3-[5-[4-(4-phenylbutoxy)phenyl]-2H-tetrazol-2-yl]propyl]-(138631-10-4)

Safety Data

• Hazardous Substances Data: 138631-10-4(Hazardous Substances Data)

Upstream product

• 138631-08-0 5-<4-(-phenylbutoxy)phenyl>-2H-tetrazole 
• 5332-06-9 4-bromobutanenitrile 
• 138631-41-1 4-(4-phenylbutoxy)benzonitrile 
• 767-00-0 4-cyanophenol 
• 65512-08-5 4-phenylbutyl methanesulfonate 

Relevant articles and documents

Development of a Series of Phenyltetrazole Leukotriene D4(LTD4) Receptor Antagonist

A hypothetical model for receptor binding of leukotriene D4 (LTD4) was deduced from conformational analysis of LTD4 and from the structure-activity relationships (SAR) of known LTD4 receptor antagonists.A new structural series of LTD4 receptor antagonists exemplified by 5--2--2H-tetrazole was designed in which a phenyltetrazole moiety was incorporated as a receptor binding equivalent of the triene unit of LTD4.A number of these phenyltetrazoles were prepared and found to possess LTD4 receptor antagonist activity.The structure-activity relationship (SAR) of this series is described.