138642-40-7Relevant academic research and scientific papers
2-Aryloxy-4-alkylaminopyridines: Discovery of novel corticotropin-releasing factor 1 antagonists
Chen, Yuhpyng L.,Obach, R. Scott,Braselton, John,Corman, Michael L.,Forman, James,Freeman, Jody,Gallaschun, Randall J.,Mansbach, Robert,Schmidt, Anne W.,Sprouse, Jeffrey S.,Tingley III, F. David,Winston, Elizabeth,Schulz, David W.
, p. 1385 - 1392 (2008/09/20)
An orally active clinical candidate of corticotropin-releasing factor 1 (CRF1) antagonist 1 showed a significant positive food effect in dog and human after oral administration. Efforts to address the food effect issue led us to explore and dis
