138642-63-4

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 6640-27-3 2-chloro-p-cresol 

Downstream Products

• 195318-63-9 methyl 2-chloro-4-methylbenzoate 
• 1190707-50-6 [(2-chloro-4-methylphenyl)ethynyl]trimethylsilane 
• 1190706-83-2 (S)-6-(2-chlorophenyl)-N-(3,4-difluorobenzyl)-7-(piperidin-3-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine trifluoroacetate 
• 1190707-52-8 (S)-tert-butyl 3-((6-(2-chloro-4-methylphenyl)-2-(3,4-difluorobenzylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)piperidine-1-carboxylate 
• 1190707-51-7 (S)-tert-butyl 3-((2-chloro-6-(2-chloro-4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)piperidine-1-carboxylate 
• 108579-27-7 ethyl 3-(2-chloro-4-methylphenyl)propanoate 
• 124244-16-2 3-(2-chloro-4-methyl-phenyl)-propionic acid 
• 174603-62-4 4-chloro-6-methyl-indan-1-one 
• 143572-60-5 methyl 4-(bromomethyl)-2-chlorobenzoate 
• 916913-65-0 methyl 2-chloro-4-{[2-{isobutyl[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}benzoate 

Relevant academic research and scientific papers

A novel approach to 3-methylindoles by a heck/cyclization/isomerization process

Chemical Equation presented A novel synthesis of 3-methyllndoles from chlorotrlflates through a Heck reaction, carbamate/aryl chloride coupling, and Isomerlzatlon sequence Is presented. The three-step sequence Is highly efficient and general, enabling the

PYRROLO[2,3-d]PYRIMIDIN-2-YL-AMINE DERIVATIVES AS PKC-THETA INHIBITORS

The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also re

Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists

A series of 4-[(2-{isobutyl[(5-methyl-2-furyl)sulfonyl]amino}phenoxy)methyl]benzoic acids and 4-({2-[isobutyl(1,3-thiazol-2-ylsulfonyl)amino]phenoxy}methyl)benzoic acids were synthesized and evaluated for their EP receptor affinities and EP1 receptor anta

Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity

Extension of the structure-activity relationship studies that led to the discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro

Amide derivatives and their therapeutic use

A compound of formula (I), wherein R1 and R2 are independently selected from chloro, fluoro, bromo, C1-6 alkyl, C1-6 alkoxy or C1-6 haloalkyl provided that both R1 and R2 are not