138657-10-0

Basic information

• Product Name: Pyridinium, 1-(5-methoxy-1-methyl-1H-benzimidazol-2-yl)-2,4,6-triphenyl-, iodide
• CAS NO: 138657-10-0
• Molecular Formula: C32H26N3O.I
• Molecular Weight: 595.482
• Mol File: 138657-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyridinium, 1-(5-methoxy-1-methyl-1H-benzimidazol-2-yl)-2,4,6-triphenyl-, iodide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridinium, 1-(5-methoxy-1-methyl-1H-benzimidazol-2-yl)-2,4,6-triphenyl-, iodide(138657-10-0)
• EPA Substance Registry System: Pyridinium, 1-(5-methoxy-1-methyl-1H-benzimidazol-2-yl)-2,4,6-triphenyl-, iodide(138657-10-0)

Safety Data

• Hazardous Substances Data: 138657-10-0(Hazardous Substances Data)

Upstream product

• 96-96-8 4-methoxy-2-nitroaniline 
• 102-51-2 4-methoxy-1,2-phenylenediamine 
• 6232-91-3 2-amino-5-methoxy-benzimidazole 
• 138657-09-7 C₃₁H₂₃N₃O 
• 74-88-4 methyl iodide 

Relevant articles and documents

NMR studies of N-(benzimidazol-2-yl)pyridinium derivatives: QSAR with the anti-leishmanial activity and their carbon-13 NMR chemical shifts

Quantitative structure-activity-relationships between the in vitro anti-leishmanial activity of N-benzimidazolyl-2,4,6-triphenylpyridinium salts 6 and pyridinium benzimidazolate betaines 7 and their 13C-NMR chemical shifts have been studied, in order to ascertain the influence of the benzimidazole substituents upon anti-leishmanial activity.The calculated 13C-chemical shifts allow the selection of a representative subset of compounds.Several new N-benzimidazolylpyridinium derivatives 6 and 7 have been prepared.Among them, 5-methoxy-1-methylbenzimidazole 21 and 6-methoxy-1-methylbenzimidazole 22 derivatives have high anti-leishmanial activity in vitro and compound 22 shows an interesting activity in vivo although host toxicity is present.