1386859-76-2

Upstream product

• 486422-59-7 {4-[(dimethylamino)sulfonyl]phenyl}boronic acid 
• 1384958-64-8 (1E,4E)-ethyl 2-amino-7-bromo-3H-benzo[b]azepine-4-carboxylate 

Relevant academic research and scientific papers

SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.