1387531-40-9

Upstream product

• 105-13-5 4-Methoxybenzyl alcohol 
• 824-94-2 p-methoxybenzyl chloride 
• 949580-77-2 6-bromomethyl-3-(3,4-dimethoxyphenyl)chromen-2-one 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 3462-97-3 (4-methoxybenzyl)triphenylphosphonium bromide 

Relevant academic research and scientific papers

Synthesis and biological evaluation of resveratrol-coumarin hybrid compounds as potential antitumor agents

Eighteen resveratrol-coumarin hybrid compounds (6 or 7-styryl-3- phenylcoumarin) were designed, synthesized and thirteen compounds were evaluated for their antitumor activities against MCF-7, HCT-28, and K562 tumor cell lines. Among them, compounds 2Z, 2E, 5E, and 7E showed varying degrees of growth inhibition of the above cell lines (IC50: 3.78-19.16 μmol/L). On the basis of the biological results, structure-activity relationships were obtained and discussed.