1387578-97-3Relevant academic research and scientific papers
Construction of an asymmetric quaternary carbon via an asymmetric aza-Claisen rearrangement and its application in the total synthesis of (+)-α-cuparenone
Nishii, Takeshi,Miyamae, Fumiaki,Yoshizuka, Makoto,Kaku, Hiroto,Horikawa, Mitsuyo,Inai, Makoto,Tsunoda, Tetsuto
scheme or table, p. 739 - 741 (2012/09/05)
Excess lithium hexamethyldisilazide (LHMDS) with LiCl prompted the asymmetric aza-Claisen rearrangement of carboxamide and retarded the decomposition of its amide enolate. The addition of these two reagents was a key step that led to the total synthesis o
