1387635-23-5Relevant academic research and scientific papers
InCl3-catalyzed [2+3] cycloaddition reaction: A rapid synthesis of 5-substituted 1H-tetrazole under microwave irradiation
Patil, Vijay S.,Nandre, Kamalakar P.,Borse, Amulrao U.,Bhosale, Sidhanath V.
experimental part, p. 1145 - 1152 (2012/05/31)
A series of 5-substituted 1H-tetrazole were efficiently prepared by InCl3 catalyzed (10 mol %) from structurally divert organic nitriles with sodium azide under the influence of microwave irradiation. The present protocol was successfully applied to the aliphatic, aryl, benzylic and heterocyclic nitriles and corresponding 5-substituted 1H-tetrazole were obtained in good to excellent yield (70-96%). This method gives remarkable advantages such as short reaction time, simple work-up procedure and economical beneficial.
