138772-14-2Relevant academic research and scientific papers
Synthesis, biological evaluation, and structure-activity relationships of novel substituted N-phenyl ureidobenzenesulfonate derivatives blocking cell cycle progression in s-phase and inducing DNA double-strand breaks
Turcotte, Vanessa,Fortin, Sébastien,Vevey, Florence,Coulombe, Yan,Lacroix, Jacques,C?té, Marie-France,Masson, Jean-Yves,C.-Gaudreault, René
, p. 6194 - 6208 (2012/08/27)
Twenty-eight new substituted N-phenyl ureidobenzenesulfonate (PUB-SO) and 18 N-phenylureidobenzenesulfonamide (PUB-SA) derivatives were prepared. Several PUB-SOs exhibited antiproliferative activity at the micromolar level against the HT-29, M21, and MCF-
ALKYLUREA DERIVATIVES ACTIVE AGAINST CANCER CELLS
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Page/Page column 24; 46, (2012/11/07)
Compounds of formula (I) : wherein A, m, n, R1, X, Y, R2, R3, R4, R5 and R6, as defined herein are provided as useful for the treatment of cancer or for the manufacture of anti-cancer agents.
