138778-08-2Relevant academic research and scientific papers
Anodic Oxidation Products of 2',5'-Dimethoxyacetanilide Derivatives, and Their Application to the Synthesis of Aminoanthraquinones
Russell, Richard A.,Longmore, Robert W.,Warrener, Ronald N.
, p. 1691 - 1704 (2007/10/02)
Anodic oxidation of simple 2',5'-dimethoxyacetanilides proceeds under mildly basic conditions to afford either monomeric or dimeric quinone bisacetals, depending on the structure of the substrate.Similarly, the oxidation of linked derivatives of 2',5'-dimethoxyacetanilides is shown to exhibit a comparable sensitivity, with non-alkylated amides being efficiently converted into bis(quinone bisacetals).The regiospecificity of acetal hydrolysis for both simple and linked quinone bisacetals is shown to be dependent upon the nature of the N-acyl group.The annelation of these hydrolysis products with the anion of 3-cyanophthalide to yield (acylamino)anthraquinones is also reported.
