138806-23-2Relevant academic research and scientific papers
Synthesis of 2'-Deoxy-&β-D-ribofuranosyl Imidazole and Thiazole C-Nucleosides
Bergstrom, Donald E.,Zhang, Peiming,Zhou, Jie
, p. 3029 - 3034 (2007/10/02)
A synthetic route to 2-carbamoyl-4-(2'-deoxy-β-D-ribofuranosyl)imidazole 3, starting from 2-deoxy-3,5-di-O-toluoyl-β-D-ribofuranosyl cyanide 4, was developed.The key steps are reduction of the cyano group of compound 4 to a formyl and subsequent condensat
AN EFFICIENT ROUTE TO C-4 LINKED IMIDAZOLE NUCLEOSIDES: SYNTHESIS OF 2-CARBAMOYL-4-(2'-DEOXY-β-D-RIBOFURANOSYL)IMIDAZOLE
Bergstrom, Donald E.,Zhang, Peiming
, p. 6485 - 6488 (2007/10/02)
The first synthesis of an imidazole C-nucleoside linked through C-4, 2-carbamoyl-4-(2'-deoxy-β-D-ribofuranosyl)imidazole was achieved by way of a nine-step sequence starting from 2-deoxy-3,5-di-O-p-toluoyl-D-erythro-pentofuranosyl chloride.
