1388136-11-5Relevant academic research and scientific papers
Synthesis of15N-labeled heterocyclesviathe cleavage of C-N bonds of anilines and glycine-15N
He, Jiwen,Zhang, Xingguo,He, Qiuqin,Guo, Hao,Fan, Renhua
, p. 5442 - 5445 (2021)
A nitrogen replacement process that directly incorporates the15N atom of glycine-15N into anilines was reported. The process involves a Csp2-N bond cleavage of anilines driven by dearomatization and a Csp3-N bond cleavage of glycine-15N driven by aromatization. A variety of15N-labeled aromatic heterocycles can be preparedviathis process.
