1388233-64-4

Basic information

• Product Name: 5-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(trifluoromethyl)benzamide
• Synonyms: 5-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(trifluoromethyl)benzamide
• CAS NO: 1388233-64-4
• Molecular Weight: 419.222
• Mol File: 1388233-64-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(trifluoromethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(trifluoromethyl)benzamide(1388233-64-4)
• EPA Substance Registry System: 5-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(trifluoromethyl)benzamide(1388233-64-4)

Safety Data

• Hazardous Substances Data: 1388233-64-4(Hazardous Substances Data)

Upstream product

• 1300857-04-8 3-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)benzamide 
• 129946-88-9 Umemoto's reagent 
• 1711-06-4 3-Methylbenzoyl chloride 
• 99-04-7 m-Toluic acid 

Relevant articles and documents

Pd(II)-catalyzed ortho trifluoromethylation of arenes and insights into the coordination mode of acidic amide directing groups

A Pd(II)-catalyzed trifluoromethylation of ortho C-H bonds with an array of N-arylbenzamides derived from benzoic acids is reported. N-Methylformamide has been identified as a crucial promoter of C-CF3 bond formation from the Pd center. X-ray characterization of the C-H insertion intermediate has revealed a rare coordination mode of acidic amides as directing groups and the origin of their capacity in directing C-H activation.